Epigenetic mechanisms of neuroplasticity and the implications for stroke recovery
نویسندگان
چکیده
منابع مشابه
Exercise-mediated locomotor recovery and lower-limb neuroplasticity after stroke.
Assumptions that motor recovery plateaus within months after stroke are being challenged by advances in novel motor-learning-based rehabilitation therapies. The use of lower-limb treadmill (TM) exercise has been effective in improving hemiparetic gait function. In this review, we provide a rationale for treadmill exercise as stimulus for locomotor relearning after stroke. Recent studies using n...
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OBJECTIVE Sleep disruption in the acute phase after stroke has detrimental effects on recovery in both humans and animals. Conversely, the effect of sleep promotion remains unclear. Baclofen (Bac) is a known non-rapid eye movement (NREM) sleep-promoting drug in both humans and animals. The aim of this study was to investigate the effect of Bac on stroke recovery in a rat model of focal cerebral...
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Gait disorders drastically affect the quality of life of stroke survivors, making post-stroke rehabilitation an important research focus. Noninvasive brain stimulation has potential in facilitating neuroplasticity and improving post-stroke gait impairment. However, a large inter-individual variability in the response to noninvasive brain stimulation interventions has been increasingly recognize...
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15 صفحه اولDynamic Brains and the Changing Rules of Neuroplasticity: Implications for Learning and Recovery
A growing number of research publications have illustrated the remarkable ability of the brain to reorganize itself in response to various sensory experiences. A traditional view of this plastic nature of the brain is that it is predominantly limited to short epochs during early development. Although examples showing that neuroplasticity exists outside of these finite time-windows have existed ...
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ژورنال
عنوان ژورنال: Experimental Neurology
سال: 2015
ISSN: 0014-4886
DOI: 10.1016/j.expneurol.2014.09.017